|
KMID : 0438219780150010025
|
|
Korea University Medical Journal
1978 Volume.15 No. 1 p.25 ~ p.45
|
|
|
Experimental Studies on Blood Ammonia with Stomal Patency after the Side-to-Side Portacaval Shunt
|
|
|
|
|
Abstract
|
|
|
Side-to-side portacaval shunts were . constructed on 8 adult mongrel dogs to evaluate the changes of body weight,_ hematologic values,. liver function tests, blood ammonias, stomal patencies and the. changes of inferior venacaval.and portal-vein pressures before and. after the shunts operations.
At autopsy after 6week of operation, 3 non patent stomal dogs are designated as group j and 5 patent stomal dogs as group I and their comparisons between the both group were observed. Results-are as follows. .
1. In both group,.:~foll owing operation._body weights revealed temporary reduction but regained the .
preoperative weights on the 4th week of operation and . maintained till 6th week.
2. In both. group, The R. B. C. , Hb, Ht, W. B. C. and platelets were decreased and failed to return to the preoperative values till the 6th week.
3. In both group, mild impairment _of hepatic functions were Aobserved._.
Albumins, . cholesterols, G. P. T. and G. O. T. (group j) were slightly decreased in comparison with the preoperative values whereas, globulin, alkaline phosphatasl~k and G. O. T. (group 1) were increased. A/G ratio was reversed. Serum bilirubin revealed no change to list.
4.- In. group, j after _6 week of operation, blood ammonia was decreased by 16.7% in comparison with the preoperative value.
In group 1 preoperative value of blood ammonia vas .12~ ug/dl. Following _operation, it grad-_. :.
ually incr and:. ter Ss week of operation rea.4hed to $56:1 dd1,. ein~ rem`+ arkable increment.
tit 4b!5
rate of 111 9%
5. In group I , inferior vena caval and portal vein pressures revealed reduction rate of 12.5% and 1. 6% respecitvely in comparison with the pre-operative values whereas, splanchnic limb pressure increased by 10. 30%.
In group inferior vena caval pressure revealed increment rate of 14% in comparison with the preoperative value whereas, splanchnic limb and portal vein pressures revealed reduction rate of 11% and 31% respectively.
|
|
|
KEYWORD
|
|
|
|
|
|
FullTexts / Linksout information
|
|
|
|
|
|
Listed journal information
|
|
|
|
|